CDC now recommends that people whose immune systems are compromised moderately to severely should receive an additional dose of mRNA COVID-19 vaccine after the initial 2 doses. Widespread vaccination is a critical tool to help stop the pandemic.

Read CDC’s statement.

What You Need to Know

• People who are moderately to severely immunocompromised are especially vulnerable to COVID-19 because they are more at risk of serious, prolonged illness.
• People who have compromised immune systems may benefit from an additional dose to make sure they have enough protection against COVID-19.
• CDC recommends people who are moderately to severely immunocompromised should receive an additional dose of mRNA COVID-19 vaccine after the initial 2 doses.

CDC recommends that people with moderately to severely compromised immune systems receive an additional dose of mRNA COVID-19 vaccine at least 28 days after a second dose of Pfizer-BioNTech COVID-19 vaccine or Moderna COVID-19 vaccine.

CDC does not recommend additional doses or booster shots for any other population at this time.
Click here for the most recent in summary on vaccine recommendations.

Interim Clinical Considerations for Use of COVID-19 Vaccines Currently Authorized in the United States
Summary of recent changes (last updated August 13, 2021):

New section on considerations for use of an additional dose of COVID-19 vaccine following a primary vaccine series

New section on considerations for use of an additional mRNA COVID-19 vaccine dose after an initial 2-dose primary mRNA COVID-19 vaccine series for immunocompromised people

This site also include downloadable PDFs of COVID-19 reference materials.

Click here to view the full summary.